Provigil® (modafinil) reduced fatigue in cancer patients receiving chemotherapy according to a study reported by Gary Morrow PhD at the 2008 ASCO meeting. Patients were asked to complete a survey on 2 occasions during the study Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners Breast cancer patients who reported a score of ≥ 2 on the Brief Fatigue Inventory (BFI) were enrolled in the study. Cancer related fatigue is that fatigue which persists even after. 'Cancer related fatigue' is not a simple symptom, but is an entity in itself, in that it is different from routine fatigue. Provigil is a central nervous system stimulant that is currently FDA-approved for treating people with narcolepsy , shift-work sleep disorde r, and sleep apnea that is associated with excessive daytime sleepiness Why did Cephalon close its Provigil Patient Assistance Program Sep 12, 2008 · Health Policy Hub A reader of this blog recently wrote to us here at provigil for cancer patients Prescription Access Litigation and reported that the Cephalon (Nasdaq:CEPH) had closed its Patient Assistance Program for Provigil, its prescription drug for Narcolepsy and other sleep disorders Related Reading: breast cancer | cancer | antidepressants Comment from: mamagl, 45-54 on Treatment for 6 months - 1 year (Patient) Published: November 17 Provigil has been very good for me Modafinil, which is commonly prescribed to manage fatigue in cancer patients, had no effect on fatigue in a new study of patients with non-small-cell lung cancer Cancer-related fatigue failed to improve significantly in patients treated with the alertness-promoting drug modafinil (Provigil), British investigators reported. Provigil prescription assistance is sponsored by Cephalon to help low-income and uninsured patients get expensive brand-name Provigil either for free or at a large discount. Cephalon's Provigil patient assistance program provigil skin picking helps with free or discount Provigil. Modafinil for Cancer Patients It is used both as a palliative and to cope with the side effects of treatment An estimated 60% of cancer patients experience fatigue , either from the disease itself or as a side effect of treatment Provigil was not designed for cancer patients, it is used mainly to treat people with narcolepsy. In Phase 1 (P1), patients received 200mg modafinil open-label once daily for 4 weeks. It has some troublesome side effects. PS Card recommends RX Access for help in the Provigil PAP application process Fatigue is the most common side effect of cancer treatment with chemotherapy, radiation therapy, or selected biologic response para que sirve provigil modifiers. Cancer-related fatigue (CRF) is often experienced with additional symptoms, including sleep disturbance, pain, and depression [ 2 – 4 ] Some drugs may have another patient information leaflet. In the randomized provigil sat test phase 3 trial, investigators studied 642 patients who were receiving chemotherapy for a variety of cancers. Rx help is available to those who meet the Provigil PAP guidelines below Cephalon's clinical program will evaluate the use of NUVIGIL as a treatment for serious medical conditions such as bipolar depression, cognition associated with schizophrenia, excessive sleepiness in medical conditions such as Parkinson's disease, and fatigue in patients who are being treated for cancer The authors describe data from 83 patients with breast or prostate cancer enrolled in a small, multi-center, randomized, double-blind, placebo-controlled trial. If you think there has been an overdose, call your poison control center or get medical care right away Common Questions and Answers about Provigil and cancer provigil Modafinil (d, l-2-[(diphenylmethyl) sulfinyl] acetamide) [ Provigil ] is a novel wake- and vigilance- promoting agent that is chemically and pharmacologically dissimilar to CNS stimulants such as the amphetamines, methylphenidate, and pemoline This latest trial found that patients taking modafinil reported a significant overall effect of the drug on fatigue (P =. In Phase 2 (P2), patients with a positive response following P1 were randomized either to an additional 4 weeks of modafinil or to placebo In patients with severe hepatic impairment, the dose of Provigil should be reduced to one-half of that recommended for patients with normal hepatic function [see Dosage and Administration and Clinical Pharmacology ] Find patient medical information for Provigil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.. Patients who were severely fatigued after their first chemotherapy treatment had less fatigue after they received Provigil than those who got a provigil memory concentration placebo Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners Provigil Prices, Coupons and Patient Assistance Programs. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider. All patients were does provigil increase concentration receiving docetaxel-based chemotherapy provigil for cancer patients (with a minimum dose of docetaxel of 50 mg/m 2 , given every 3 weeks) Well-designed, randomized, controlled clinical trials are still needed to further elucidate the precise role of this drug in the care of patients with cancer. Specifically, large placebo-controlled trials with modafinil must be conducted in patients with cancer, with specific attention paid to pain control, depression, cognitive function, and adverse effects Provigil (modafinil) is a medication that is sometimes prescribed to patients with MS-related fatigue. A recent. Get free or discount Provigil by applying for Cephalon's Provigil patient assistance program (PAP). Nuvigil is the 2nd generation of Provigil and the manufacturer has lowered the price to get everyone "switched" before the patent on Provigil expires in 2011 June 4, 2008 (Chicago) -- The narcolepsy drug Provigil may help to relieve the debilitating fatigue often experienced by cancer patients undergoing chemotherapy, new research suggests.  Cancer treatment–related fatigue generally improves after therapy is completed, but some level of fatigue may persist for months or years provigil for cancer patients following treatment.. Provigil (modafinil) is a member of the CNS stimulants drug class and is commonly used for Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome and Shift Work Sleep Disorder Specifically, large placebo-controlled trials with modafinil must be conducted in patients with cancer, with specific attention paid to pain control, depression, cognitive function, and how long does it take for provigil to get out of your system adverse effects Provigil has one the one hand deprived consumers of a more affordable prescription and on the assistance hand told uninsured patients prescription assistance that they're out of luck halfway through the year Cancer related fatigue (CRF) is a highly prevalent and highly significant entity among patients with cancer. 03). Provigil is more expensive and I actually had more side effects with Provigil. Scores on a validated fatigue-assessment questionnaire differed by 2/10 of a point in favor of modafinil, a margin that did not achieve statistical significance The labeling change comes less than one month after the FDA issued a warning on another Cephalon drug, Fentora, which is a used to treat extreme pain in cancer patients; the FDA said several patients had accidentally overdosed on the drug while using it for non approved uses.. In a clinical trial for narcolepsy, 74 of the 934 patients (8%) who received PROVIGIL dropped out compared to 3% of patients that received placebo Fatigue is the most common symptom patients with cancer experience, with a prevalence rate that exceeds 60% in many studies.